Clinical Score Identifies Th2-Driven Endotype in Bullous Pemphigoid
The BPDAI urticaria/erythema subscore correlates with IL-13 levels and JAK-STAT signaling, suggesting a role for targeted immunotherapies.
Brolucizumab Preserves Vision Better Than Laser in Diabetic Retinopathy
The Phase 3 CONDOR trial shows brolucizumab 6 mg maintains visual acuity and regresses disease more effectively than panretinal laser.
Vascular Procedure Costs Rise 32% as Hospital Margins Erode
A study of five common vascular interventions shows that rising labor and supply costs are significantly outpacing payer reimbursement.
Normalization Choice Impacts Molecular Rejection Diagnosis in Kidney Transplants
Standardized data processing maintains high diagnostic accuracy for antibody and T cell-mediated rejection in allograft biopsies.
Psychosocial Screening at Intake Increases Comprehensive Care in Pediatric Psychiatry
Identifying family risk profiles through standardized tools helps clinicians tailor interventions and improve resource allocation for youth.
International Consensus Defines Standards for Forensic Mental Health Systems
A Delphi study involving 23 experts establishes 12 guiding principles and 43 core components to unify global forensic psychiatric care.
Children's Hospitals Delay Effective Surge Strategies Despite Tracking Occupancy
A national study shows a disconnect between capacity metrics and the operational triggers used to mitigate inpatient strain.
Bereaved Family ACP Participation Boosts Own Planning and Interpersonal Trust
Participation in a loved one's end-of-life planning increases the likelihood of survivors' own advance care planning and reduces anxiety.
Common Genetic Variants Linked to Acute Myeloid Leukemia Risk and Survival
A meta-analysis identifies four new germline loci associated with specific cytogenetic subtypes and clinical outcomes in myeloid malignancy.
Botulinum Toxin Increases Eyelid Height More Than Levator Shortening
A cohort study shows orbicularis oculi injections improve palpebral fissure height by 3.5 mm with fewer complications than surgery.
Rural Detention Centers Drive High-Acuity EMS Volume and Long-Distance Transfers
A cross-sectional analysis reveals that 43% of emergency transports from a Georgia detention facility require 40-mile tertiary transfers.
Dupilumab Resolves Airway Mucus Plugs and Reduces Radiodensity in Asthma
A longitudinal CT analysis shows dupilumab clears 91% of existing mucus plugs and alters the physical composition of remaining obstructions.