Daily reporting on clinically relevant studies for busy physicians

Blood In Vitro Study

VWF Deficiency Drives Angiodysplasia via Angiopoietin-2 Dysregulation

New research identifies a molecular pathway linking von Willebrand factor deficiency to gut angiodysplasia, suggesting a targeted therapeutic…

May 29, 2026
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Trial Watch

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New Guidelines

  1. Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock 2026

    SCCM and ESICM launch 2026 guideline for Sepsis and Septic Shock Management

    SCCM/ESICM · Sepsis and septic shock management · 2026
  2. 2026 AHA/ACC/ACCP/ACEP/CHEST/SCAI/SHM/SIR/SVM/SVN Guideline for the Evaluation and Management of Acute Pulmonary Embolism in Adults: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines

    AHA and ACC launch 2026 guideline for Acute Pulmonary Embolism in Adults

    AHA/ACC · Acute Pulmonary Embolism in Adults · 2026
  3. 2026 Guideline for the Early Management of Patients With Acute Ischemic Stroke

    AHA and ASA launch 2026 guideline for Acute Ischemic Stroke management

    AHA/ASA · Acute ischemic stroke management · 2026
  4. Clinical Policy: Critical Issues in the Management of Adult Patients Requiring Endotracheal Intubation in the Emergency Department

    ACEP launches 2025 clinical policy for Endotracheal Intubation in the Emergency Department

    ACEP · Endotracheal intubation in the emergency department · 2025
  5. INTEGRATE: international guidelines for the algorithmic treatment of schizophrenia

    LANCETP launches 2025 guideline for Algorithmic Treatment of Schizophrenia

    LANCETP · Algorithmic treatment of schizophrenia · 2025
  6. Updated Appropriate Use Criteria for Amyloid and Tau PET: A Report from the Alzheimer’s Association and Society for Nuclear Medicine and Molecular Imaging Workgroup

    AA and SNMMI launch 2025 guideline for Amyloid and Tau PET Appropriate Use Criteria

    AA/SNMMI · Amyloid and Tau PET Appropriate Use Criteria · 2025
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Latest

  1. CT-Detected White Matter Disease Signals Higher Stroke/Dementia Risk Than MRI-Only Findings

    CT-Detected White Matter Disease Signals Higher Stroke/Dementia Risk Than MRI-Only Findings

    Neurology · May 28, 2026
  2. Multiomic Analysis Reveals CTCL Progression Mechanisms, Identifies Therapeutic Targets

    Multiomic Analysis Reveals CTCL Progression Mechanisms, Identifies Therapeutic Targets

    Blood · May 28, 2026
  3. Smoking Cessation Reduces Dementia Risk, But Weight Gain May Attenuate Benefit

    Smoking Cessation Reduces Dementia Risk, But Weight Gain May Attenuate Benefit

    Neurology · May 27, 2026
  4. True Refractoriness to Caplacizumab in iTTP Is Rare

    True Refractoriness to Caplacizumab in iTTP Is Rare

    Blood · May 27, 2026
  5. Itraconazole Inhibits OXPHOS in AML, Targets Therapy-Resistant Leukemic Stem Cells

    Itraconazole Inhibits OXPHOS in AML, Targets Therapy-Resistant Leukemic Stem Cells

    Blood · May 27, 2026
  6. ERV Reactivation Drives C4b-Mediated Synaptic Pruning in Autism Models

    ERV Reactivation Drives C4b-Mediated Synaptic Pruning in Autism Models

    Neuron · May 27, 2026
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