IV Iron Linked to Improved Survival, Anemia Recovery in Acute Infection
A retrospective cohort study suggests intravenous iron administration during acute infection does not worsen outcomes and may offer benefits.
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True Refractoriness to Caplacizumab in iTTP Is Rare
A multicenter study found that delayed platelet recovery in iTTP patients on caplacizumab is usually due to confounding factors, not true…
CT-Detected White Matter Disease Signals Higher Stroke/Dementia Risk Than MRI-Only Findings
A large cohort study reveals distinct prognostic implications for covert cerebrovascular disease based on imaging modality.
2026 Guideline for the Early Management of Patients With Acute Ischemic Stroke
Acute ischemic stroke management
Prehospital Whole Blood Does Not Reduce 30-Day Mortality Over Components
A large-scale trial found no significant difference in 30-day mortality between prehospital whole blood and component transfusions for trauma.
Low-Dose Buprenorphine Sustains Ketamine's Antisuicidal Effects in MDD
A randomized trial indicates sublingual buprenorphine extends ketamine's rapid reduction of suicidal ideation in major depressive disorder.
Trial Watch
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Weight Loss Intervention Safe in Older AF Patients, But Does Not Improve Symptoms
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Inhaled Treprostinil Slows Lung Function Decline, Reduces Clinical Worsening in IPF
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4% Tetrasodium EDTA Lock Reduces CVAD Complications in ICU Adults
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Tezepelumab Reduces Oral Corticosteroid Use in Severe Asthma
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Prehospital Whole Blood Does Not Reduce 30-Day Mortality Over Components
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Favipiravir Safe, Well-Tolerated for Mild-to-Moderate Lassa Fever
New Guidelines
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SCCM and ESICM launch 2026 guideline for Sepsis and Septic Shock Management
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AHA and ACC launch 2026 guideline for Acute Pulmonary Embolism in Adults
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AHA and ASA launch 2026 guideline for Acute Ischemic Stroke management
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ACEP launches 2025 clinical policy for Endotracheal Intubation in the Emergency Department
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LANCETP launches 2025 guideline for Algorithmic Treatment of Schizophrenia
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EUSEM launches 2025 guideline for Acute Pain Management in Emergency Situations
Latest
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French NOMADMUS Cohort Details AQP4+NMOSD, MOGAD Trends
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Itraconazole Inhibits OXPHOS in AML, Targets Therapy-Resistant Leukemic Stem Cells
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Orca-T Immunotherapy Enriches Regulatory-Like T-Cells Early Post-Transplant
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IL-1β Signaling Drives Aggressive TCF3::HLF B-ALL and Bone Lesions
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TTP: EEG Delta Activity Correlates With Transient Aphasia, Resolves With Treatment
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QCT Fibrosis Score Thresholds Predict Transplant-Free Survival in IPF