Daily reporting on clinically relevant studies for busy emergency and critical care physicians

Blood Cohort Study

IV Iron Linked to Improved Survival, Anemia Recovery in Acute Infection

A retrospective cohort study suggests intravenous iron administration during acute infection does not worsen outcomes and may offer benefits.

May 28, 2026
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Trial Watch

  1. Weight Loss Intervention Safe in Older AF Patients, But Does Not Improve Symptoms

    Weight Loss Intervention Safe in Older AF Patients, But Does Not Improve Symptoms

    JAMA · May 21, 2026
  2. Inhaled Treprostinil Slows Lung Function Decline, Reduces Clinical Worsening in IPF

    Inhaled Treprostinil Slows Lung Function Decline, Reduces Clinical Worsening in IPF

    New England Journal of Medicine · May 20, 2026
  3. 4% Tetrasodium EDTA Lock Reduces CVAD Complications in ICU Adults

    4% Tetrasodium EDTA Lock Reduces CVAD Complications in ICU Adults

    JAMA · May 20, 2026
  4. Tezepelumab Reduces Oral Corticosteroid Use in Severe Asthma

    Tezepelumab Reduces Oral Corticosteroid Use in Severe Asthma

    Lancet Respiratory Medicine · May 20, 2026
  5. Prehospital Whole Blood Does Not Reduce 30-Day Mortality Over Components

    Prehospital Whole Blood Does Not Reduce 30-Day Mortality Over Components

    New England Journal of Medicine · May 20, 2026
  6. Favipiravir Safe, Well-Tolerated for Mild-to-Moderate Lassa Fever

    Favipiravir Safe, Well-Tolerated for Mild-to-Moderate Lassa Fever

    Nature Medicine · May 17, 2026
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New Guidelines

  1. Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock 2026

    SCCM and ESICM launch 2026 guideline for Sepsis and Septic Shock Management

    SCCM/ESICM · Sepsis and septic shock management · 2026
  2. 2026 AHA/ACC/ACCP/ACEP/CHEST/SCAI/SHM/SIR/SVM/SVN Guideline for the Evaluation and Management of Acute Pulmonary Embolism in Adults: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines

    AHA and ACC launch 2026 guideline for Acute Pulmonary Embolism in Adults

    AHA/ACC · Acute Pulmonary Embolism in Adults · 2026
  3. 2026 Guideline for the Early Management of Patients With Acute Ischemic Stroke

    AHA and ASA launch 2026 guideline for Acute Ischemic Stroke management

    AHA/ASA · Acute ischemic stroke management · 2026
  4. Clinical Policy: Critical Issues in the Management of Adult Patients Requiring Endotracheal Intubation in the Emergency Department

    ACEP launches 2025 clinical policy for Endotracheal Intubation in the Emergency Department

    ACEP · Endotracheal intubation in the emergency department · 2025
  5. INTEGRATE: international guidelines for the algorithmic treatment of schizophrenia

    LANCETP launches 2025 guideline for Algorithmic Treatment of Schizophrenia

    LANCETP · Algorithmic treatment of schizophrenia · 2025
  6. Guidelines for the management of acute pain in emergency situations

    EUSEM launches 2025 guideline for Acute Pain Management in Emergency Situations

    EUSEM · Acute pain management in emergency situations · 2025
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Latest

  1. French NOMADMUS Cohort Details AQP4+NMOSD, MOGAD Trends

    French NOMADMUS Cohort Details AQP4+NMOSD, MOGAD Trends

    Neurology · May 28, 2026
  2. Itraconazole Inhibits OXPHOS in AML, Targets Therapy-Resistant Leukemic Stem Cells

    Itraconazole Inhibits OXPHOS in AML, Targets Therapy-Resistant Leukemic Stem Cells

    Blood · May 27, 2026
  3. Orca-T Immunotherapy Enriches Regulatory-Like T-Cells Early Post-Transplant

    Orca-T Immunotherapy Enriches Regulatory-Like T-Cells Early Post-Transplant

    Blood · May 26, 2026
  4. IL-1β Signaling Drives Aggressive TCF3::HLF B-ALL and Bone Lesions

    IL-1β Signaling Drives Aggressive TCF3::HLF B-ALL and Bone Lesions

    Blood · May 26, 2026
  5. TTP: EEG Delta Activity Correlates With Transient Aphasia, Resolves With Treatment

    TTP: EEG Delta Activity Correlates With Transient Aphasia, Resolves With Treatment

    Neurology · May 26, 2026
  6. QCT Fibrosis Score Thresholds Predict Transplant-Free Survival in IPF

    QCT Fibrosis Score Thresholds Predict Transplant-Free Survival in IPF

    American Journal of Respiratory and Critical Care Medicine · May 25, 2026
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