Waveform-Derived 60-Second ROSC Definition Accurately Identifies Transient Events

Despite advances in resuscitation science, cardiac arrest remains a formidable clinical challenge with high mortality [1, 2]. A key goal during resuscitation is achieving return of spontaneous circulation (ROSC), but the clinical picture is often complicated by periods of transient ROSC followed by rearrest [3, 4]. These dynamic fluctuations make it difficult to accurately measure the quality of cardiopulmonary resuscitation (CPR) and evaluate the effectiveness of interventions in real time [5, 6]. Without reliable methods to track these events, refining clinical protocols and improving patient outcomes is significantly hindered, underscoring the need for validated measurement tools for use in post-resuscitation care [7, 8].