The Briefing
Continuous newsroom coverage of clinically relevant evidence — newest first.
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Changing Negative Beliefs Drives Depression Relief During Psychotherapy
A longitudinal analysis confirms that improving negative self-beliefs during psychotherapy forecasts long-term symptom reduction.
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Suicidality at Focal Epilepsy Diagnosis Predicts Treatment Resistance
Adults expressing suicidality when diagnosed with focal epilepsy face a nearly threefold higher risk of failing antiseizure medications.
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Experts Recommend Lithium and Antidepressants to Prevent ECT Relapse
A Delphi consensus of international experts outlines structured maintenance therapies, including continuation ECT for high-risk patients.
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International Consensus Urges Early Surgery for Hypothalamic Hamartomas
A new Delphi consensus from 17 epilepsy centers establishes standardized protocols for diagnosing and managing rare hypothalamic hamartomas.
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Vasopressor Weaning Sequence Does Not Alter Hypotension Risk
A meta-analysis of 2,280 patients reveals no overall difference in hypotension or secondary outcomes when weaning norepinephrine first.
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Structural Brain Network Modeling Identifies Three ADHD Biotypes
Mapping structural brain deviations against a developmental baseline links specific ADHD clinical profiles to distinct neural circuits.
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Vasopressor Timing Does Not Predict 90-Day Mortality in Septic Shock Study
A retrospective cohort study of 4,699 patients reveals that time to vasopressor initiation is not independently associated with survival
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Trial: Higher Bupivacaine Doses Do Not Improve Nerve Block Headache Relief
A randomized trial finds that low-dose, unilateral sphenopalatine ganglion blocks are as effective as higher doses for acute headaches
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Study Shows Presyncope Carries Same 30-Day Cardiac Risk as Syncope
Emergency physicians underestimate presyncope risk, admitting these patients less often despite identical 30-day cardiac event rates
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Study: One Dexamethasone Dose Matches Two for Pediatric Asthma
A retrospective cohort study of 2,063 children shows a single dose of dexamethasone is as effective as two doses for asthma exacerbations
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Study: 63 Percent of Older Adults Take Inappropriate Medications
A cross-sectional study reveals that despite low medication complexity, nearly two-thirds of older adults use potentially harmful drugs
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Cardiac Arrest Study: Supraglottic Airways Outperform Intubation
A national analysis reveals supraglottic devices offer higher first-pass success and better rescue rates than repeated intubation attempts