American Journal of Respiratory and Critical Care Medicine
15 articles tagged "American Journal of Respiratory and Critical Care Medicine"
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QCT Fibrosis Score Thresholds Predict Transplant-Free Survival in IPF
Specific quantitative CT fibrosis score changes identify idiopathic pulmonary fibrosis patients at higher risk for worse outcomes.
Key Factors Drive Tidal Recruitment/Derecruitment in Spontaneously Breathing ARDS
A study identifies specific physiological and radiological determinants of lung injury in ARDS patients on pressure support ventilation.
Gut Microbiota Linked to IPF Severity, Survival, and Treatment Response
A study in 411 patients with idiopathic pulmonary fibrosis identifies specific gut microbial associations with disease progression and treatment.
Higher Rocuronium Dose Linked to Increased First-Attempt Intubation Success in ICU
A secondary analysis suggests that rocuronium doses above 1.2 mg/kg improve intubation success in critically ill ICU patients.
Texas Abortion Ban Linked to Increased Critical Illness in High-Risk Pregnant Patients
A retrospective cohort study in Texas found that a 2021 abortion ban correlated with higher rates of critical illness, sepsis, and infection.
COPD Bronchoalveolar Lavage Reveals Specific Immune Cell Shifts Linked to Disease Severity
Single-cell sequencing identifies expanded macrophage, monocyte, and T-lymphocyte populations associated with airflow limitation and gas exchange.
Dupilumab Reduces COPD Hospitalizations, ED Visits, and Corticosteroid Use
A pooled analysis of two phase 3 trials shows dupilumab significantly lowers healthcare utilization and corticosteroid burden in COPD patients.
AD109 Reduces Apnea-Hypopnea Index in PAP-Intolerant OSA Patients
An oral combination of aroxybutynin and atomoxetine significantly improved objective respiratory metrics over 26 weeks.
Tezepelumab Reduces Exacerbations, Improves Lung Function in Diverse Severe Asthma Cohort
A real-world phase 4 study shows tezepelumab's effectiveness and safety across various severe asthma phenotypes and underrepresented patient groups.
Astegolimab Reduces COPD Exacerbations in Broad Patient Population
A pooled analysis of two trials shows astegolimab significantly lowers moderate/severe exacerbation rates in patients with frequent COPD.
Specific Patient Profiles Face Up to 30% Risk of Severe Asthma Progression
A large Danish cohort study identifies key risk factors and patient characteristics associated with progression from mild-to-moderate to severe asthma
Extra-Pulmonary TB Linked to Persistent Lung Function Deficits
A new study reveals that extra-pulmonary tuberculosis survivors experience lasting respiratory impairment, similar to pulmonary TB.