Waveform-Derived 60-Second ROSC Definition Accurately Identifies Transient Events
A prospective validation study confirms a specific defibrillator waveform criterion reliably detects transient return of spontaneous circulation.
CBD's Pain Modulation Effects Vary by Opioid Dosing Timing in OUD Patients
A crossover study reveals cannabidiol's impact on pain sensitivity is dependent on whether opioid agonist treatment has been administered.
MMAE for cSDH: Resolution Trajectories and Functional Outcomes Quantified
A large multicenter study details the temporal patterns of hematoma reduction and functional recovery after middle meningeal artery embolization.
Plasma Proteins Predict Multiple Sclerosis Risk and Disease Severity
An integrated genetic-proteomic analysis identifies specific circulating proteins associated with MS risk and progression, offering potential…
Hippocampal Subfield Atrophy Links to Cognitive Decline in Healthy Aging
A study in healthy Indian adults identifies specific hippocampal subfield volume reductions in older age associated with poorer learning and memory.
AI Algorithm Continuously Monitors Inspiratory Muscle Effort, Patient-Ventilator Synchrony
A new AI algorithm offers a noninvasive, real-time method for assessing inspiratory muscle pressure and detecting dyssynchronies in mechanically…
ICP Monitoring Linked to Lower 30-Day Mortality in Kenyan Severe TBI Patients
A retrospective cohort study in a low- and middle-income country found intracranial pressure monitoring associated with reduced mortality.
Helicopter Transport Expands ECPR Access for Rural Refractory Cardiac Arrest
A HEMS-facilitated ECPR pathway safely extends advanced resuscitation to rural areas, maintaining neurologic outcomes comparable to ground transport.
ITBS Improves Fibromyalgia Symptoms; D-Cycloserine Augments Depressive Symptoms Only
A randomized trial found intermittent theta-burst stimulation significantly reduced fibromyalgia symptoms, but adjunctive D-Cycloserine only…
Astrocytic Enzyme Regulates Vascular Stability in Alzheimer's Disease Model
Targeting soluble epoxide hydrolase in astrocytes reduced vascular amyloid burden and preserved vasomotion in amyloidosis mice.
Massive Transfusion Reduces Vancomycin Levels in Swine Model
A swine study indicates that prophylactic vancomycin may become subtherapeutic after four units of whole-blood resuscitation.
GIP Infusion Does Not Improve Glycemic Control in Type 2 Diabetes
A 6-week subcutaneous GIP infusion, alone or with semaglutide, did not meet its primary glycemic target in patients with type 2 diabetes.