AHA and ACC launch 2026 guideline for Acute Pulmonary Embolism in Adults
A new clinical categorization system for acute PE refines risk stratification, enabling more precise management and expanding outpatient treatment.
Autism Subtypes Linked to Distinct Brain Connectivity and Biological Pathways
A cross-species neuroimaging study identifies two replicable autism subtypes with specific functional connectivity patterns and biological underpinnin
Simvastatin Rescues Cognitive Impairment in Alzheimer's Model via Epigenetic and Synaptic Pathways
A preclinical study in mice identifies specific molecular mechanisms by which simvastatin may improve cognitive function in Alzheimer's disease.
Military Blood Supply Insufficient for Large-Scale Combat Operations
Simulation reveals current Forward Resuscitative Surgical Detachment blood strategies, even with walking blood banks, fail rapidly under high casualty
Favipiravir Safe, Well-Tolerated for Mild-to-Moderate Lassa Fever
A phase 2 trial in Nigeria provides pharmacokinetic data and supports favipiravir as an alternative to ribavirin for Lassa fever.
Somatic Symptoms, Sensory Dysregulation Are Core to PTSD Presentation
Current PTSD treatments often fall short because they overlook the central role of physical sensations and sensory processing.
Cameroon Football Reveals Gaps in Cardiac Screening, Emergency Preparedness
A cross-sectional study highlights critical deficiencies in cardiovascular screening and sudden cardiac arrest response among football teams in Camero
ED Nudge Strategy Increases Naltrexone Prescribing for Alcohol Misuse
A multicomponent emergency department protocol significantly raised naltrexone initiation for patients with alcohol-related diagnoses.
Refining Lower Limb TMS: Identifying MEPs in Resting Ipsilateral Muscles
This study quantifies motor evoked potentials in the non-target resting leg, offering methodological clarity for transcranial magnetic stimulation.
IBD Inflammation Augments CHIP Risk, APE1/Ref-1 Identified as Therapeutic Target
A new study links inflammatory bowel disease to increased clonal hematopoiesis of indeterminate potential, identifying a specific molecular pathway.
Demographics Influence Etiology in 2,052 Patients With Late-Onset Seizures
A multicenter study finds that while stroke remains common, neurodegeneration and unexplained causes dominate the geriatric epilepsy profile.
Selective HDAC6 Inhibition Improves Motor Function in Preclinical ALS Models
A CNS-penetrant small molecule restores protein clearance and axonal transport, reducing neurofilament levels and TDP-43 pathology.