AL Amyloidosis Prognostic Models Lag Behind Treatment Advances
Current risk stratification tools for AL amyloidosis do not reflect improved patient outcomes with modern daratumumab-based regimens.
Contextual Fit Drives Physical Activity Program Success in Disadvantaged Schools
A review of 16 interventions identifies key implementation conditions for effective physical activity programs in socio-economically disadvantaged…
Delayed Awakening After Cardiac Arrest: Prognostic Implications and Recovery Potential
A scoping review highlights variable definitions and the potential for good neurological recovery despite delayed awakening after OHCA.
Non-Ischemic Dilated Cardiomyopathy: Higher Prevalence, Complex Genetics
Updated estimates suggest non-ischemic dilated cardiomyopathy affects 1 in 220, driven by diverse genetic and environmental factors.
Endometriosis and Ovarian Cancer: Balancing Risk, Prevention, and Fertility
A review clarifies the nuanced management of ovarian cancer risk in endometriosis, integrating molecular insights and treatment strategies.
Global Efforts Advance Human Rights Protections for Older Adults' Mental Health
International bodies and national initiatives are establishing frameworks to safeguard the dignity and mental well-being of the aging population.
Somatic Symptoms, Sensory Dysregulation Are Core to PTSD Presentation
Current PTSD treatments often fall short because they overlook the central role of physical sensations and sensory processing.
High-Impact Sports Linked to 4-15-Fold Increased MND/ALS Risk
A scoping review identifies a significant association between professional participation in high-impact sports and elevated motor neurone disease risk
Neuroimaging Biotypes May Guide MDD Treatment, Improve Remission
Functional MRI-derived circuit profiles could personalize major depressive disorder therapy, potentially doubling remission rates.
Maternal Genetic Variants Linked to Aneuploid Conception Identified in Review
A systematic review identifies specific maternal genetic variants associated with aneuploid conceptions, offering new insights for infertility diagnos
FDA-Approved Therapies and Multidisciplinary Care Extend Survival in ALS
New clinical data highlight the role of genetic testing and targeted therapies in managing progressive motor neuron degeneration.
Commercial AI for Lung Cancer Screening Lacks Full Guideline Alignment
An analysis of 16 CE-marked products reveals gaps in managing cystic lesions and a lack of prospective evidence for patient outcomes.