Early Bradycardia Predicts Need for Positive Pressure Ventilation in Newborns
An observational study quantifies heart rate response to tactile stimulation and identifies early bradycardia as a marker for advanced resuscitation.
4% Tetrasodium EDTA Lock Reduces CVAD Complications in ICU Adults
A multicenter, cluster-randomized trial shows 4% t-EDTA locking fluid decreases a composite of CVAD-associated events, primarily catheter occlusions.
Selective Early PDA Pharmacotherapy Feasible in Extremely Preterm Infants
A pilot randomized trial demonstrates the feasibility of a targeted medical approach for patent ductus arteriosus in infants under 26 weeks'.
Gram-Negative Bacteria Dominate Neonatal Infection Deaths in LMICs
A multicountry study identifies Klebsiella pneumoniae and Acinetobacter baumannii as leading causes of neonatal infection mortality.
UK and Ireland Neonatal Stroke Incidence: 9.0 per 100,000 Live Births
A new surveillance study details the epidemiology, clinical patterns, and short-term outcomes of neonatal stroke in the UK and Ireland.
UK Neonatal Stroke Incidence: 9.0 per 100,000 Live Births, Varied Presentations
A new surveillance study details the incidence, clinical features, and initial management of neonatal stroke in the UK and Ireland.
Identical EEG Bursts Signal Severe Loss of Brain Network Complexity
A multi-model study identifies identical burst suppression as a default state of simplified excitatory networks in irreversible coma.
Mothers Report Gaps in Prenatal Counseling and Neonatal Realities
A study of 64 mothers finds that 32 percent experienced inconsistencies between antenatal consultations and neonatal intensive care.
Early Probiotics Reduce Mortality in Extremely Preterm Infants
A Norwegian registry study of 1,596 neonates finds early probiotic use lowers death risk and may reduce surgical necrotizing enterocolitis.
Multi-Echo T2* MRI Identifies Neonatal Hemochromatosis via Extrahepatic Iron Patterns
Pancreatic and thyroid siderosis on MRI distinguishes neonatal hemochromatosis from other liver failure causes with 92.3% accuracy.
Automated MRI Segmentation Establishes Brain Volume Norms for Very Preterm Infants
Sex-stratified reference ranges for 26 brain regions provide a clinical baseline to identify developmental deviations at term-equivalent age.
Symptom-Based Dosing Reduces Discharge Time in Neonatal Opioid Withdrawal
A cluster randomized trial shows symptom-based dosing shortens medical readiness for discharge when paired with the Eat, Sleep, Console model.