IV Iron Linked to Improved Survival, Anemia Recovery in Acute Infection
A retrospective cohort study suggests intravenous iron administration during acute infection does not worsen outcomes and may offer benefits.
French NOMADMUS Cohort Details AQP4+NMOSD, MOGAD Trends
A nationwide registry in France provides real-world data on diagnostic and therapeutic shifts, and disease activity in AQP4+NMOSD and MOGAD.
True Refractoriness to Caplacizumab in iTTP Is Rare
A multicenter study found that delayed platelet recovery in iTTP patients on caplacizumab is usually due to confounding factors, not true…
Orca-T Immunotherapy Enriches Regulatory-Like T-Cells Early Post-Transplant
A specific T-cell subset, CD4+CD25-FOXP3+Helios+ T conventional cells, is enriched early after Orca-T and correlates with later immune activation.
IL-1β Signaling Drives Aggressive TCF3::HLF B-ALL and Bone Lesions
A new study identifies interleukin-1β as a key driver in a highly aggressive B-cell acute lymphoblastic leukemia subtype.
TTP: EEG Delta Activity Correlates With Transient Aphasia, Resolves With Treatment
A case report details how left temporal lateralized rhythmic delta activity (LRDA) on EEG tracked fluctuating aphasia in TTP, resolving with targeted
QCT Fibrosis Score Thresholds Predict Transplant-Free Survival in IPF
Specific quantitative CT fibrosis score changes identify idiopathic pulmonary fibrosis patients at higher risk for worse outcomes.
Naloxone Linked to Improved Survival in PEA Out-of-Hospital Cardiac Arrest
A retrospective cohort study suggests prehospital naloxone administration is associated with better survival to discharge for OHCA patients.
Prone Positioning Use Surged During Pandemic, Declined Post-COVID
A North American study reveals a significant increase in prone positioning for hypoxemic patients during the pandemic, followed by a notable decrease.
Key Factors Drive Tidal Recruitment/Derecruitment in Spontaneously Breathing ARDS
A study identifies specific physiological and radiological determinants of lung injury in ARDS patients on pressure support ventilation.
Proximity-Based Lung Allocation Policy May Worsen Geographic Disparities
A new study suggests that increasing donor-candidate proximity in lung allocation could reduce donor availability and disadvantage harder-to-match.
ECMO Escalation in ARDS: Prevalence, Mortality, and Hospital Volume Impact
A large Chinese cohort study details the incidence and outcomes of venovenous ECMO escalation in ARDS, highlighting mortality risks.