Systematic Vagus Nerve Stimulation Increases Sensitivity for Detecting Vocal Cord Palsy
Adding a final vagal check after thyroid dissection achieved 100% sensitivity for nerve injury, identifying cases missed by distal testing.
Synuclein Status Shows Limited Correlation With Brain Microstructure in Early Parkinson's
A study of 462 patients finds that positive alpha-synuclein assays do not reflect widespread neurodegeneration on diffusion MRI.
Digital Therapeutic App Reduces Chronic Tinnitus Distress in Randomized Trial
A mobile application delivering cognitive behavioral therapy significantly improved Tinnitus Handicap Inventory scores over 24 weeks.
Platelet Transfusion Linked to Higher Mortality in Sepsis Patients
A retrospective study finds transfusions increase ICU stay and thrombosis risk while failing to raise counts in half of septic patients.
Psychological Factors Predict High-Impact Chronic Pain in Sickle Cell Disease
A prospective study of 90 patients shows that pain catastrophizing and low self-efficacy correlate with sustained functional impairment.
Cell-Specific Gene Expression Analysis Identifies Schizophrenia Risk Drivers
Researchers mapped 466 causal genes across eight brain cell types, pinpointing MAU2 and PPP1R13B as high-priority therapeutic targets.
C1q-Mediated Synaptic Pruning Drives Postoperative Cognitive Decline in Murine Models
Surgical trauma triggers NF-κB signaling and C1q-dependent microglial phagocytosis of hippocampal synapses, leading to memory impairment.
Prophylactic Antiemetics Fail to Reduce Opioid-Induced Nausea in Prehospital Trauma
A prospective study of 205 HEMS patients shows no benefit for routine intravenous ondansetron or isopropanol aromatherapy.
Awake Mapping for Grade 2 Glioma Reduces Intractable Epilepsy Burden
Extensive resection of IDH-mutant tumors improves seizure freedom and return-to-work rates, particularly for insular lesions.
Prenatal SRI Exposure Linked to Altered Fetal Brain and Placental Growth
MRI data show reduced hippocampal volume and cortical folding in fetuses exposed to antidepressants or high maternal depression scores.
Taekwondo and Football 5-a-Side Show Highest Injury Risk at Paris Paralympics
Prospective surveillance of 4,450 athletes reveals significant sex-based and sport-specific variations in injury burden and illness rates.
Ivermectin Fails to Improve Outcomes in Hospitalized COVID-19 Patients
A randomized trial shows no benefit for organ support-free days or survival in critically and noncritically ill patients.