Distributed HABIT-ILE Dosing Matches Massed Therapy for Bilateral Cerebral Palsy
Spreading 90 hours of intensive bimanual and lower extremity therapy over 15 weeks yields functional gains equivalent to 3-week programs.
Antipsychotics and Antiemetics Drive Pediatric Drug-Induced Dystonia
A study of 79 children finds most reactions occur within 72 hours of exposure and respond rapidly to parenteral biperiden.
Bilateral Dynamic CT Uses Contralateral Wrist to Diagnose Scapholunate Injury
Using the patient's healthy wrist as an internal control eliminates the need for external reference sets in 4D computed tomography.
Dual-Nerve Coaptation Improves Sensory Recovery in DIEP Flap Reconstruction
A prospective cohort study finds that two nerve repairs enhance tactile recovery and psychosocial well-being compared to a single repair.
Postural Control Deficits Drive Gait Dysfunction in Huntington's Disease
Wearable sensor data show that balance impairments explain up to 39 percent of gait variance and emerge during the pre-manifest stage.
Early Probiotics Reduce Mortality in Extremely Preterm Infants
A Norwegian registry study of 1,596 neonates finds early probiotic use lowers death risk and may reduce surgical necrotizing enterocolitis.
Delaying Substance Use Until Age 21 Linked to 83% Lower Polysubstance Risk
A national survey of 92,233 adults shows that early initiation before age 18 significantly increases the risk of multiple concurrent addictions.
Current Screening Tools for Head and Neck Cancer Social Risks Lack Breadth
A scoping review finds that most clinical instruments for social determinants of health focus narrowly on financial distress.
Elevated hsCRP and Oxidative Stress Predict Musculoskeletal Injury Risk
A prospective study of US Army trainees finds systemic biomarkers rise in the week preceding clinical diagnosis of musculoskeletal injury.
Plasmodium knowlesi Adapts In Vitro to Infect Duffy-Negative Erythrocytes
A chimeric gene allows the zoonotic parasite to bypass the Duffy-antigen receptor, suggesting potential for wider geographic spread.
MEF2C Network Drives Glomerular Endothelial Proliferation in Diabetic Kidney Disease
Multiomics analysis reveals how SGLT2 inhibitors may stabilize endothelial gene networks to prevent neovascularization and cell death.
Simple Thoracostomy Shows Higher Success Rate Than Needle Decompression in Cadavers
A crossover study using fresh human cadavers found that simple thoracostomy achieved faster and more complete pleural decompression.