AI Model Predicts Glioblastoma Infiltration Beyond Visible Tumor Margins
A prospective trial validates an AI tool using biopsies to map microscopic tumor spread and predict survival in glioblastoma patients.
Self-Mixed Morphine Gel Reduces Pain and Systemic Opioid Use in Cancer
A 0.125% topical morphine gel mixed by patients reduced pain scores by 61.8% and significantly lowered daily oral morphine requirements.
Bitemporal ECT and rTMS Plus SSRIs Reduce Suicidal Ideation
A network meta-analysis of 58 trials finds nonconvulsive brain stimulation alone is ineffective for suicidal ideation without medication.
Community CPR Training Increases Bystander Response but Not Defibrillator Use
A study of 6,280 cardiac arrests shows high training rates boost chest compressions while device use remains stagnant at less than 1%.
Buprenorphine Initiation Succeeds in 71% of Opioid-Tolerant Cancer Patients
A retrospective study shows transdermal and buccal buprenorphine reduce pain scores with low rates of precipitated withdrawal.
Cilta-cel Induces Universal MRD Negativity in High-Risk Smoldering Multiple Myeloma
A phase 2 trial shows 100% of patients achieved deep, sustained responses without prior induction therapy or disease progression.
Large Language Models Reduce Radiology Reporting Time and Transcription Errors
A multicenter study finds LLMs faster than conventional speech recognition but notes inconsistent efficiency and new error types.
AI Model Predicts Axillary Response Using Baseline Mammography
A deep learning tool identifies nodal conversion after neoadjuvant therapy, potentially reducing unnecessary axillary dissections.
Simultaneous Cochlear Implants Improve Long-Term Sound Localization
Adolescents with simultaneous bilateral implants show superior spatial hearing compared to those with a brief sequential delay.
TNM-9 Staging Shows Limited Prognostic Accuracy in Nasopharyngeal Carcinoma
A retrospective study finds the ninth edition TNM system lacks strong survival discrimination when patients receive PET/CT imaging.
Advanced MRI Detects Occult Neuronal Loss in Asymptomatic MCA Occlusion
Soma and neurite density imaging reveals microstructural gray matter damage in stroke-free patients with chronic arterial occlusion.
Isolated MPFL Reconstruction Stabilizes Patella Despite High Femoral Anteversion
Patients with femoral torsion over 30 degrees and minimal maltracking achieved stability without derotational osteotomy in a 2-year study.