Platelet mTOR Pathway Drives Neuropathogenesis in Cerebral Malaria
A new study identifies the mechanistic target of rapamycin (mTOR) in platelets as a key mediator of brain injury in experimental cerebral malaria.
Autonomic Burden Linked to Cognitive Fluctuations in Lewy Body Dementia
A longitudinal study finds autonomic symptom severity correlates with neuropsychiatric burden and reduced caregiver quality of life.
Anterior Temporal Atrophy Precedes Semantic Dementia Symptoms by Five Years
Large-scale MRI analysis identifies a prolonged prodromal phase and quantifies the prevalence of incidental anterior temporal lobe loss.
Amateur Soccer Heading Linked to Acute Elevations in Neural Damage Biomarkers
A prospective study found that heading in amateur soccer acutely increases blood levels of p-tau217 and S100B, with dose-response relationships.
Cervical Spinal Cord Injury Linked to Higher Depression Risk Than Lower-Level Injuries
A nationwide cohort study reveals patients with cervical SCI face a significantly elevated risk of depression compared to those with thoracic/lumbar.
Adenoviral Protein Reactivity Linked to Guillain-Barré Syndrome After COVID-19
Patients with post-infection or post-vaccination GBS show heightened antibody responses to adenoviruses, suggesting a shared trigger.
Stereotactic Radiosurgery Improves Tumor Control, Overall Outcomes for Older VS Patients
A retrospective study indicates stereotactic radiosurgery significantly reduces vestibular schwannoma progression and improves neurological outcomes.
Continuous EEG Enhances Detection of Post-Stroke Epilepsy Predictors
A retrospective study shows continuous EEG significantly improves identification of epileptiform activity and prediction of post-stroke epilepsy.
Cingulum Hippocampus White Matter Integrity Linked to Suicide Attempts in Bipolar Disorder
Reduced fractional anisotropy in the cingulum hippocampus, mediated by impulsivity, associates with suicide attempts in bipolar disorder.
Accelerometer Data Predicts Dementia Risk in Older Adults
Objective sleep-wake cycle metrics from wearables modestly enhance dementia risk prediction, comparable to APOE genotype.
AA and SNMMI launch 2025 guideline for Amyloid and Tau PET Appropriate Use Criteria
New guidelines expand appropriate use of amyloid and tau PET, particularly for eligibility and monitoring of amyloid-targeting therapies.
Alzheimer's Association launches 2024 guideline for Alzheimer's disease and related dementias
New guidance empowers primary care clinicians with a structured, patient-centered approach to diagnostic evaluation, testing, counseling.