Syrinx Shunt Outcomes Vary by Type: Revision Risk vs. Early Neurological Benefit
A retrospective study compares syringopleural, syringosubarachnoid, and syringoperitoneal shunts, detailing revision rates and neurological improvemen
Tea Polyphenols Mitigate Brain Changes, Anxiety in Aged Diabetic Rats
A preclinical study in aged T2DM rats suggests tea polyphenol intervention may improve hippocampal structure, function, and behavior.
Diffuse White Matter Abnormalities Do Not Predict Long-Term Dementia Risk
A 10-year study finds that 'dirty-appearing' white matter lacks the prognostic weight of focal hyperintensities in older adults.
Lamotrigine-Topiramate Duotherapy Increases Congenital Malformation Risk Fourfold
A large registry study identifies a significant risk increase for specific antiseizure drug combinations used during the first trimester.
Biallelic EIPR1 Variants Cause Neurodevelopmental Syndrome and Neutropenia
Defects in endosomal recycling and dense core vesicle biogenesis drive a spectrum of microcephaly, ataxia, and spasticity.
Frontal AVMs Alter fMRI Language Lateralization, Requiring Clinical Caution
A retrospective study indicates that arteriovenous malformations in the frontal lobe significantly affect fMRI-based language lateralization indices.
Cutamesine Mitigates Hippocampal Damage in In Vitro Ischemia Models
A sigma-1 receptor agonist reduced neuronal cell death and cellular stress markers in rat hippocampal slices exposed to oxygen-glucose deprivation.
Cluster Headache Prevalence Rises as Female Incidence Surpasses Males in Norway
A 14-year registry study shows the historical male predominance in cluster headache is vanishing as female incidence rates climb.
African Ancestry Parkinson’s Disease Linked to Distinct GBA1 and LRRK2 Variants
Genetic screening of 710 African ancestry cases reveals that common European risk variants are absent, replaced by population-specific mutations.
Sternal Vibration Plus Mindfulness Improves Body Awareness, White Matter in Trauma
A study in trauma-exposed adults found sternal vibration combined with mindfulness meditation enhanced interoceptive awareness and increased neurite.
Occipitotemporal White Matter: Redefining Inferior Longitudinal Fasciculus Components
A combined cadaveric dissection and diffusion tensor imaging study clarifies the anatomical boundaries and subcomponents of key visual and cognitive.
APOE ε2 and ε4 Drive Alzheimer's Risk Through Distinct Molecular Pathways
A multicohort proteomic analysis reveals allele-specific protein signatures influencing Alzheimer's disease risk and progression.