CTBS to Right DLPFC Reduces Heavy Drinking Relapse Risk in AUD Over 12 Months
Continuous theta-burst stimulation to the right DLPFC lowered heavy-drinking relapse risk in AUD over 12 months in a randomized trial.
Younger Age, Autoimmune Disease Linked to Recurrent, Bilateral Facial Palsy
A retrospective study identifies specific risk factors for recurrent and bilateral facial palsy in Bell's Palsy and Ramsay Hunt Syndrome patients.
Simvastatin Rescues Cognitive Impairment in Alzheimer's Model via Epigenetic and Synaptic Pathways
A preclinical study in mice identifies specific molecular mechanisms by which simvastatin may improve cognitive function in Alzheimer's disease.
Refining Lower Limb TMS: Identifying MEPs in Resting Ipsilateral Muscles
This study quantifies motor evoked potentials in the non-target resting leg, offering methodological clarity for transcranial magnetic stimulation.
Demographics Influence Etiology in 2,052 Patients With Late-Onset Seizures
A multicenter study finds that while stroke remains common, neurodegeneration and unexplained causes dominate the geriatric epilepsy profile.
Selective HDAC6 Inhibition Improves Motor Function in Preclinical ALS Models
A CNS-penetrant small molecule restores protein clearance and axonal transport, reducing neurofilament levels and TDP-43 pathology.
Intravenous Magnesium Sulfate Reduces Rescue Analgesia for Acute Headache
A randomized trial finds adjunctive magnesium sulfate increases treatment success and patient satisfaction, despite pain reduction not meeting clinica
Multimodal AI System Matches Clinicians in Simulated Telehealth Diagnostics
A new AI system, multimodal AMIE, integrates diverse data types to achieve high diagnostic accuracy and conversational quality in simulated telehealth
ALS Subtypes Show Distinct Immune Remodeling, Linking Blood Changes to Spinal Cord Damage
A new study details specific immune cell dynamics and molecular programs in ALS, revealing distinct patterns across disease subtypes.
Thrombectomy Improves Functional Independence in Medium-Vessel Occlusion Stroke
A randomized trial shows endovascular thrombectomy increases functional independence but also raises symptomatic intracranial hemorrhage risk in mediu
SSPOP Mutations Linked to Pediatric Epilepsy and Developmental Disorders
Researchers identify pathogenic variants in a supposed pseudogene, expanding the diagnostic landscape for unexplained neurodevelopmental delay.
Long-Duration Levodopa Response Distinguishes Parkinson's, Predicts Outcomes
A study details how sustained levodopa motor improvement helps differentiate parkinsonian syndromes and offers prognostic insights for PD.