Pediatric Cannabis Hyperemesis Protocol Increases Capsaicin Use and Lowers Haloperidol Dosing
A standardized algorithm shifted prescribing patterns for adolescent cannabis hyperemesis without altering admission rates or length of stay.
Simultaneous Bilateral Cochlear Implants Preserve Spatial Hearing into Adolescence
Early synchronous auditory input prevents permanent localization deficits that persist despite years of bilateral device use.
Simultaneous Cochlear Implants Improve Long-Term Sound Localization
Adolescents with simultaneous bilateral implants show superior spatial hearing compared to those with a brief sequential delay.
Cerebral Oximetry Fails to Improve 2-Year Outcomes in Preterm Infants
A phase 3 trial of 1,601 infants shows no reduction in death or disability when using oximetry to guide early postnatal care.
Pediatric Knife Fatalities Linked to Deprivation and Prior Social Service Contact
A five-year review of 145 deaths in England identifies high rates of pre-hospital mortality and significant psychosocial vulnerabilities.
Risk-Adapted Therapy Improves Survival in Pediatric Acute Myeloid Leukemia
Refined stratification using measurable residual disease and genetics increased 3-year overall survival to 83.9% in a large cohort.
Routine Prednisolone Does Not Prevent Coronary Lesions in Kawasaki Disease
A large randomized trial shows that adding steroids to standard therapy does not protect the coronary arteries of unselected children.
Obesity and Prediabetes Rates Rise Among Northern Great Plains Children
A multi-year screening of American Indian students shows obesity rates exceeding 40% and a doubling of prediabetes prevalence.
GNAO1-Related Disorders Follow Non-Degenerative Course Despite Progressive Movement Symptoms
A longitudinal study of 66 patients shows cognitive stability while severe cases face functional burden from worsening movement disorders.
Chronotherapeutic Protocol Advances Circadian Timing and Extends Adolescent Sleep
A two-week intervention using light-modulating glasses and scheduling increased weeknight sleep by 47 minutes in high school students.
Open-Source Models Accurately Identify Pediatric Pneumonia in Radiology Reports
Large language models achieve F1 scores up to 0.97, surpassing traditional machine learning in classifying free-text chest X-ray reports.
Resilience Alters Symptom Networks Linking Bullying to Depression in Adolescents
Network analysis reveals that low resilience strengthens the ties between social exclusion and depressive symptoms like anhedonia.