Homozygous LGI1 Variant Linked to Severe Developmental and Epileptic Encephalopathy
A case report details a homozygous LGI1 gene variant causing drug-resistant epilepsy and profound developmental delay, contrasting with typical.
TTP: EEG Delta Activity Correlates With Transient Aphasia, Resolves With Treatment
A case report details how left temporal lateralized rhythmic delta activity (LRDA) on EEG tracked fluctuating aphasia in TTP, resolving with targeted
Plantar Agraphesthesia Signals Lower Limb Cortical Sensory Loss in Corticobasal Syndrome
A case report details how plantar agraphesthesia can indicate cortical sensory deficits in the lower limb, even without hand involvement.
Cerebrotendinous Xanthomatosis Drives Recurrent Stroke After PFO Closure
A 23-year-old's recurrent M1 occlusion reveals how metabolic drivers of premature atherosclerosis can mimic or coexist with structural defects.
Prefrontal Cortex Origin for Rhythmic Ictal Nonclonic Hand Motions
Intracerebral recordings show that specific hand motions often linked to temporal lobe epilepsy can originate in the middle frontal gyrus.
Xq28 Duplication Involving MECP2 Drives Multisystemic X-Linked Disability
A familial case report identifies a six-gene duplication at Xq28 causing severe neurological and cutaneous symptoms in males.
Auricular Vagus Nerve Stimulation Manages Refractory Sympathetic Hyperactivity Post-Hemorrhage
Adjunctive neuromodulation improved tachypnea and consciousness while reducing polypharmacy in a patient with intracerebral hemorrhage.
Host Antibodies and Bacterial Heteroresistance Drive Phage Therapy Failure
Pre-existing anti-prophage antibodies and bacterial subpopulations with reduced susceptibility may neutralize therapeutic bacteriophages.
Endovascular Stent-Graft Repairs Iatrogenic Subclavian Vein Injury
A 60-year-old patient maintains vessel patency two years after emergency endovascular treatment for a life-threatening venous perforation.
Guillain-Barré Syndrome Presents as Catatonic Stupor in Schizophrenia Case
Diminished tendon reflexes and albuminocytologic dissociation distinguish neurologic paralysis from psychiatric immobility.
Kennedy Infant Death Accelerated Neonatal Research and Halved Mortality Rates
The 1963 loss of Patrick Bouvier Kennedy catalyzed federal funding that transformed respiratory distress syndrome into a survivable condition.
Pseudomonas oryzihabitans Causes Carotid Pseudoaneurysm After Respiratory Infection
A 78-year-old patient developed a life-threatening internal carotid artery lesion three weeks after an untreated common cold.