Sickle Cell Trait Not Linked to Overall Mortality or Cardiovascular Disease
A large UK Biobank study finds sickle cell trait does not increase all-cause death or cardiovascular events, but associates with diabetes, kidney…
Successful HSCT Slows Brain Volume Loss in Adults With Sickle Cell Disease
A cohort study indicates that successful hematopoietic stem cell transplant is associated with preserved brain volume in adults with SCD.
Plain X-rays and Physical Exam Reliably Screen Pediatric Thoracolumbar Injuries
A multicenter study suggests dedicated spinal X-rays and physical exam can reduce unnecessary CT scans in children with potential spinal trauma.
Brazilian Study Pinpoints Persistent Critical Illness Onset at ICU Day 15
A large cohort study in Brazil identifies the transition to persistent critical illness at 15 days, impacting resource utilization.
Microsurgery Practice Patterns Shift with Innovation, Legislation Over Four Decades
A single-surgeon analysis of over 5,000 free flaps reveals how technical advances and health policy shape reconstructive trends.
Plasma p-tau217, Cognition, APOE4 Predict Alzheimer's Dementia Risk in SCD
A multimodal approach combining readily available biomarkers accurately identifies individuals with subjective cognitive decline at high risk for Alzh
MMAE for cSDH: Resolution Trajectories and Functional Outcomes Quantified
A large multicenter study details the temporal patterns of hematoma reduction and functional recovery after middle meningeal artery embolization.
Hippocampal Subfield Atrophy Links to Cognitive Decline in Healthy Aging
A study in healthy Indian adults identifies specific hippocampal subfield volume reductions in older age associated with poorer learning and memory.
ICP Monitoring Linked to Lower 30-Day Mortality in Kenyan Severe TBI Patients
A retrospective cohort study in a low- and middle-income country found intracranial pressure monitoring associated with reduced mortality.
Helicopter Transport Expands ECPR Access for Rural Refractory Cardiac Arrest
A HEMS-facilitated ECPR pathway safely extends advanced resuscitation to rural areas, maintaining neurologic outcomes comparable to ground transport.
Unhealthy Diet Linked to T17-High Asthma in Puerto Rican Youth
A study in Puerto Rican children and adolescents found an unhealthy dietary pattern increases the odds of T17-high asthma.
Low-Level FLT3-ITD Microclones Increase Relapse Risk in AML
A post-hoc analysis reveals that FLT3-ITD microclones carry a similar relapse risk to macroclones in young adults with acute myeloid leukemia.