ECPR May Improve Survival in Pediatric Out-of-Hospital Cardiac Arrest
A multicenter registry study finds higher survival and neurologic recovery rates with extracorporeal support despite wide confidence intervals.
Restrictive Sepsis Resuscitation Shows No Long-Term Functional Deficits
A randomized trial finds similar cognitive and physical outcomes at 12 months for restrictive versus liberal fluid strategies in sepsis.
Non-Intubated ECMO Failure Linked to Seven-Fold Increase in 90-Day Mortality
An international cohort study finds that while avoiding mechanical ventilation during ECMO is feasible, failure carries high mortality risks.
Multiarm Platform Evaluates Traumatic Wound Care During War in Ukraine
Researchers implement a multistage protocol to test devices and therapies for infected wounds amid rising antimicrobial resistance.
Troponin I to T Ratio Distinguishes Acute Necrosis From Chronic Injury
A multicohort study finds the troponin ratio identifies lethal cell death and improves differentiation of type 1 and 2 myocardial infarction.
Elective Microaxial Flow Pump Does Not Improve High-Risk PCI Outcomes
A randomized trial finds no clinical benefit and a potential mortality signal with routine mechanical unloading during complex revascularization.
Microaxial Flow Pump Fails to Improve Outcomes in High-Risk PCI
A randomized trial of 300 patients shows elective left ventricular unloading does not reduce major adverse events at 12 months.
Critical Illness Linked to Significant Income Loss and Unemployment
A nationwide cohort study of 582,341 survivors reveals that over 10% face catastrophic financial decline despite universal coverage.
Paramedic Decisions to Withhold Trauma Resuscitation Match Autopsy Findings
A retrospective review of 90 traumatic cardiac arrest cases shows high diagnostic specificity in field assessments of non-survivable injury.
Automated Software Matches Clinician Accuracy in Peri-operative Echocardiography
A multicenter study shows high agreement between AI-driven analysis and expert measurements for ejection fraction and valvular disease.
Survival Improves for Leukemia Patients Requiring Mechanical Ventilation in the ICU
An individual participant data meta-analysis of 2003 patients shows declining mortality for ventilated adults with acute leukemia.
Status Epilepticus Mortality Rises in the United States Since 2007
A 22-year analysis of CDC data reveals increasing death rates and significant racial and regional disparities in status epilepticus.