Structured Exercise and Resistance Training Safe During ECMO Support
A pilot study of 20 patients shows that intensive twice-daily rehabilitation correlates with improved functional performance and survival.
Ketamine Does Not Reduce 28-Day Mortality Compared With Etomidate
A randomized trial of 2,365 critically ill adults found no survival benefit for ketamine, despite a higher rate of cardiovascular collapse.
Early Plasma Reduces Mortality in Traumatic Intracranial Hemorrhage
A retrospective study of 6,183 patients shows a 5% absolute survival drop for every 10-minute delay in plasma during the first half hour.
Indirect Expenses Account for 86 Percent of Trauma Resuscitation Costs
A time-driven activity-based costing analysis of 134 patients shows the average 17-minute resuscitation costs $3,628.
RRT Configuration Does Not Impact Complication Rates in VA-ECMO Patients
A retrospective study finds no significant differences in infection or bleeding between integrated and parallel renal replacement circuits.
Low Diaphragm Thickening Fraction at One Hour Predicts Noninvasive Ventilation Failure
Bedside ultrasound of the diaphragm after 60 minutes of support identifies patients likely to require endotracheal intubation.
Noninvasive Fascial Traction Increases Primary Closure Rates in Open Abdomens
Adding a traction device to negative pressure therapy reduces the 12-month incisional hernia risk from 63.1% to 14.1%.
Targeted Therapies and Prognostic Scoring Improve Acute Liver Failure Outcomes
Early etiology-specific intervention and validated scoring systems are essential to optimize survival before advanced encephalopathy occurs.
Temperature Management Linked to Lower Brain Disability After In-Hospital Arrest
A nationwide cohort study finds targeted cooling reduces the risk of specialist-certified permanent neurological impairment by 15 percent.
Age, Rhythm, and Low-Flow Duration Predict Neurological Recovery After ECPR
A 14-year cohort study identifies specific predictors to help clinicians select cardiac arrest patients for extracorporeal resuscitation.
Dexmedetomidine Linked to Lower Mortality in ICU Patients With Delirium
A retrospective analysis of two large databases shows reduced in-hospital and one-year mortality for delirious patients given the sedative.
Subanesthetic Ketamine Improves Depressive Symptoms in Critically Ill Adults
A retrospective study finds three days of low-dose ketamine reduces sadness in ICU patients with minimal hemodynamic impact.