Age, Sex, and Initial Diagnosis Shape Mental Disorder Trajectories
A large Danish cohort study details how initial diagnosis, age, and sex influence diagnostic shifts and healthcare utilization.
Lower Oxygen Saturation Target Reduces Pediatric Hospital Stay, Oxygen Therapy
A multicenter trial suggests targeting 88% peripheral oxygen saturation in children with acute respiratory illness shortens hospitalizations.
Percutaneous Cryoablation Reduces Pain and Volume in Umbilical Endometriosis
A retrospective study of 17 patients shows high satisfaction and significant symptom relief with an outpatient interventional approach.
FDA-Approved Therapies and Multidisciplinary Care Extend Survival in ALS
New clinical data highlight the role of genetic testing and targeted therapies in managing progressive motor neuron degeneration.
Gene Expression Score Predicts Survival in Myelofibrosis
A 24-gene signature derived from stem cells identifies high-risk patients missed by current clinical and mutation-based scoring systems.
JMJD1C Deficiency Drives Pathogenic Antibody Production in Heparin-Induced Thrombocytopenia
Loss of the histone demethylase JMJD1C triggers B-cell hyperactivation and the production of platelet-activating antibodies.
FGF14 Repeat Expansions Identified in Patients with Parkinson's Disease
Long-read sequencing reveals that a genetic variant linked to ataxia also occurs in patients meeting clinical criteria for Parkinson's.
Acupuncture and Herbal Formula Improve Visual Acuity in Optic Atrophy
Combining acupuncture with Jieyu Huoxue Formula reduces blood viscosity and increases peak systolic velocity to protect the optic nerve.
Extracorporeal Limb Perfusion Does Not Exacerbate Bleeding in Porcine Trauma Model
A study of Lower Extremity Extracorporeal Distal Revascularization shows stable clot integrity despite uncontrolled vascular injuries.
Tirzepatide Reduces Major Kidney Events More Than Dulaglutide
In patients with type 2 diabetes and cardiovascular disease, tirzepatide lowered the risk of renal outcomes by 23% over four years.
Commercial AI for Lung Cancer Screening Lacks Full Guideline Alignment
An analysis of 16 CE-marked products reveals gaps in managing cystic lesions and a lack of prospective evidence for patient outcomes.
Cerebrotendinous Xanthomatosis Drives Recurrent Stroke After PFO Closure
A 23-year-old's recurrent M1 occlusion reveals how metabolic drivers of premature atherosclerosis can mimic or coexist with structural defects.