Intravenous Tocilizumab Stabilizes Severe Pediatric Neuroinflammation Within 72 Hours
A retrospective study shows rapid clinical improvement and intracranial pressure reduction in children with refractory CNS inflammation.
Systemic Steroids Accelerate Symptom Resolution in Orbital Cellulitis
An American Academy of Ophthalmology review finds steroids safe but notes inconsistent effects on hospital stay and surgical rates.
Oral PCS499 Improves Skin Activity and Ulcer Healing in Necrobiosis Lipoidica
A phase 2 trial of a deuterated pentoxifylline analog shows 50% of patients achieved clear or almost clear status with no serious safety concerns.
Dorsal Preservation Shows Early Aesthetic Gains Over Conventional Rhinoplasty
A seven-year cohort study finds dorsal preservation improves six-month cosmetic scores, though long-term outcomes converge by one year.
Patient-Provided Video Footage Influences Pediatric Trauma Management Decisions
Reviewing video of injury mechanisms altered imaging and specialist consultation plans in over half of pediatric emergency cases.
Systematic Protocols Identify and Treat True Resistant Hypertension
True resistant hypertension affects 10% of treated patients and carries a 10.3% absolute risk increase in cardiovascular death.
Radiomics Predicts Survival in Colorectal Liver Metastases Treated with TACE
Machine learning models using baseline imaging intensity and longitudinal changes stratify survival risk and identify lesion response.
2C-B Shows Empathogenic and Psychedelic Effects with Low Cardiovascular Strain
A crossover trial compares 30 mg of 2C-B to MDMA and psilocybin, finding similar emotional empathy and a shorter five-hour duration.
Maintenance Pembrolizumab and Radiotherapy Improve Outcomes in Oligometastatic Renal Cell Carcinoma
A pooled analysis of phase 2 trials shows a hazard ratio of 0.57 for progression-free survival when adding immunotherapy to local therapy.
Gut Microbiome Signatures Improve Nasopharyngeal Carcinoma Detection
Metagenomic analysis identifies microbial markers that enhance the diagnostic accuracy of Epstein-Barr virus DNA for nasopharyngeal cancer.
Retinal Imaging AI Screens for Six Systemic Metabolic and Endocrine Diseases
A multitask framework identifies diabetes, hypertension, and osteoporosis from fundus photos, showing high negative predictive value in primary care.
Outpatient Oncology Records Lack Goals-of-Care Documentation for Most Older Adults
A retrospective study of 7,743 patients found that only 43% had documented goals-of-care conversations in their electronic health records.