Network Connectivity Drives Individual Variation in Emotional Memory
Large-scale fMRI study finds distributed neural networks, not isolated amygdala activity, predict how emotional arousal enhances recall.
Endovascular Stent-Graft Repairs Iatrogenic Subclavian Vein Injury
A 60-year-old patient maintains vessel patency two years after emergency endovascular treatment for a life-threatening venous perforation.
Vuzix Head-Mounted Device Scores Highest in Prehospital Stroke Triage Simulation
A comparative study finds neurologists prefer head-mounted video quality while paramedics favor smartphone usability for remote triage.
Adolescent Opioid Harms Double Despite Reduced Emergency Department Prescribing
A decade-long study of 1.2 million visits shows that cutting pediatric opioid prescriptions did not prevent a rise in clinical harms.
Pyramidal Cell Hypofunction Predicts Psychosis Conversion in High Risk Patients
Biophysical modeling of auditory biomarkers suggests that excitatory deficits, not interneuron dysfunction, drive the transition to psychosis.
Most Validated Radiomics Models Lack Sufficient Training Data
A systematic review of high-impact journals finds 90% of machine learning models are undertrained, risking unreliable clinical predictions.
Periarticular Injection Reduces Opioid Use After Knee Infection Surgery
A retrospective study of 309 patients shows local anesthetic infiltration lowers pain scores without increasing 12-month reinfection risk.
Structured Exercise and Resistance Training Safe During ECMO Support
A pilot study of 20 patients shows that intensive twice-daily rehabilitation correlates with improved functional performance and survival.
SIRT5 Deficiency Drives Cardiac Fibrosis via Metabolic Shift in Mice
Loss of SIRT5 in cardiac fibroblasts triggers a glycolytic shift that accelerates heart failure, identifying a potential metabolic target.
Early Dopamine Loss Drives Memory Deficits in Alzheimer's Mouse Model
Dysfunction in dopamine neurons projecting to the lateral entorhinal cortex precedes neurodegeneration and impairs associative memory.
Inconsistent ALS Trial Analytics Increase False Positive Risk
A review of 45 trials shows that statistical method choice can swing treatment effect estimates and risk advancing ineffective therapies.
For-Profit Trauma Centers Increase Redundancy but Fill Critical Access Gaps
Geospatial analysis shows for-profit centers serve 43 million people, often overlapping with existing nonprofit trauma infrastructure.