Hippocampal Ripples Coordinate Cortical Planning Sequences in Epilepsy Patients
High-resolution intracranial recordings show that hippocampal ripples and neural replay drive the assembly of complex cognitive solutions.
Abdominal Contractions Drive Brain Motion and Fluid Clearance in Mice
A hydraulic link between the abdomen and cranium suggests physical activity mechanically facilitates interstitial fluid drainage.
Shared Mitochondrial Pathways Identified Across 23 Neurodevelopmental Risk Genes
Researchers used CRISPR to map how diverse genetic mutations converge on common molecular targets, allowing for drug testing in animal models.
Early Dopamine Loss Drives Memory Deficits in Alzheimer's Mouse Model
Dysfunction in dopamine neurons projecting to the lateral entorhinal cortex precedes neurodegeneration and impairs associative memory.
Grammatical Boundaries Limit Word Prediction Precision in the Human Brain
Neural responses to word unpredictability decrease at major phrase boundaries, suggesting language processing prioritizes structure over raw statistic
Intracortical Implant Enables Paralyzed Patients to Type 22 Words Per Minute
By decoding attempted finger movements, a neuroprosthesis allows patients with tetraplegia to type on a virtual QWERTY keyboard.
Brain Imaging Maps How Deep Brain Stimulation Alters Parkinson's Circuits
Extensive functional MRI data from 14 patients reveals that cortical connectivity patterns can predict clinical outcomes of stimulation.