Zorevunersen Cuts Convulsive Seizures in Children With Dravet Syndrome
The investigational antisense therapy reduced convulsive-seizure frequency by up to 90.91% and improved adaptive behavior over 36 months.
Executive Function Drivers of Autism Social Deficits Shift With Age
While executive function consistently impacts social skills in autism, the specific cognitive domains involved change as patients age.
Hybrid Dialectical Behavior Therapy Reduces Suicidal Ideation in Adolescents
A year-long trial shows combining online and offline DBT improves emotional regulation and depressive symptoms in self-injuring youth.
Pediatric Lumbar Puncture Simulation Boosts Skills but Relies on Time-Based Practice
A review of 17 studies shows simulation training improves trainee knowledge, but most programs lack objective clinical outcome measures.
Family Resilience Buffers Depression Risk in Caregivers of Children With Autism
Specific family dynamics like communication and social support mitigate the psychological impact of social alienation in Chinese parents.
Recent Infection Increases Childhood Stroke Risk; No Link Found for Vaccination
A population-based study finds that infection within 60 days more than doubles stroke risk in children, while vaccination shows no link.
Post-Traumatic Depression Persists in Youth Over One Year
Nearly 40% of trauma-exposed youth show clinically significant depression acutely, with most symptoms persisting at one year without remission.
Maps 80 Youth Mental Health Assessment Tools, Finding Critical Gaps
A scoping review of 80 outcome measurement instruments reveals a complete lack of validated tools for young adults aged 19 to 24.
International Consensus Urges Early Surgery for Hypothalamic Hamartomas
A new Delphi consensus from 17 epilepsy centers establishes standardized protocols for diagnosing and managing rare hypothalamic hamartomas.
Study: One Dexamethasone Dose Matches Two for Pediatric Asthma
A retrospective cohort study of 2,063 children shows a single dose of dexamethasone is as effective as two doses for asthma exacerbations