REM Sleep EEG Slowing Linked to Cholinergic Denervation in Older Adults
Specific REM sleep electroencephalogram patterns correlate with brain cholinergic integrity, potentially aiding early diagnosis in Alzheimer's disease
Bone Marrow Iron Predicts Mortality in Cirrhosis with Normal Liver Iron
Vertebral R2* relaxometry identifies a high-risk subgroup of patients with cirrhosis facing a fourfold increase in five-year mortality.
Focal Brain Lesions Pinpoint Common OCD Network and Treatment Targets
A systematic review identifies a shared brain network in lesional and primary OCD, aligning with neuroimaging and neuromodulation sites.
Cryoablation Reduces Umbilical Endometriosis Pain and Volume in Outpatient Study
Percutaneous image-guided cryoablation achieved 82% complete pain relief and 73% volume reduction for umbilical endometriosis.
High Antiplatelet Resistance, Elevated von Willebrand Factor in Vascular Surgery Patients
A new study reveals a high prevalence of antiplatelet resistance, particularly to clopidogrel, and elevated von Willebrand factor in patients undergoi
Habenula Hyperconnectivity in Autism Linked to Social Deficits
A large-scale rs-fMRI study identifies specific habenula functional connectivity alterations in autistic individuals, impacting social motivation.
Age, Sex, and Initial Diagnosis Shape Mental Disorder Trajectories
A large Danish cohort study details how initial diagnosis, age, and sex influence diagnostic shifts and healthcare utilization.
Percutaneous Cryoablation Reduces Pain and Volume in Umbilical Endometriosis
A retrospective study of 17 patients shows high satisfaction and significant symptom relief with an outpatient interventional approach.
FGF14 Repeat Expansions Identified in Patients with Parkinson's Disease
Long-read sequencing reveals that a genetic variant linked to ataxia also occurs in patients meeting clinical criteria for Parkinson's.
Pediatric Fibula Harvest Carries High Risk of Ankle Valgus and Nerve Palsy
A 27-year review identifies the Age-Residual Fibula Index as a key predictor for donor-site morbidity in skeletally immature patients.
Breast GPA Predicts Intracranial Progression and Survival in Breast Cancer
A large cohort study links local brain control to overall survival, identifying tumor subtype and performance status as key predictors.
Children Witness Nearly Ten Percent of US Violent Deaths and Suicides
A CDC surveillance analysis reveals that most child-witnessed fatal events occur in homes and involve firearms or domestic conflict.