Genetic Risk and Social Deprivation Drive Regional Drug Use Clusters
A Swedish study of 5,983 districts finds that family genetic risk and community deprivation explain most geographic variation in addiction.
Medicaid Expansion Linked to Lower Mortality in Young Adult Dialysis Patients
A cohort study shows a 1.8 percentage point drop in one-year mortality for young adults starting dialysis after Medicaid expansion.
Reduced Visit Pressure Increases Diagnosis Rates in Primary Care
A study of 191,269 visits shows that relieving schedule constraints allows physicians to address more new and chronic clinical issues.
ACL Reconstruction Triples 20-Year Risk of Total Knee Arthroplasty
A study of 135,881 patients shows a 2.44% absolute risk of knee replacement two decades after surgery, rising with meniscal involvement.
Redlining and Modern Loan Denials Drive Chicago Firearm Homicides
Historical housing maps and current economic discrimination act as independent, measurable factors in urban firearm violence disparities.
CSF Tau Biomarkers Associate With Cognitive Impairment in ALS
Elevated cerebrospinal fluid tau levels correlate with cognitive deficits in ALS, though postmortem TDP-43 burden remains a stronger driver.
Early Cystography After Bladder Repair Reduces Catheter Time and Infections
Imaging within seven days of traumatic bladder repair safely shortens catheterization and lowers infection rates without missing leaks.
Beti-cel Gene Therapy Sustains Transfusion Independence for Up to Ten Years
Long-term data show 90.2% of phase 3 patients achieved transfusion independence with stable hemoglobin and improved iron homeostasis.
Palliative Care Reduces Hospital Death Risk in Multiple Sclerosis
A large cohort study finds neurology oversight drops sharply before death, while rural patients face higher hospital mortality rates.
Nurse-Led School CPR Program Multiplies Community Training Reach
Students using low-cost manikins trained an average of 2.4 family members, significantly expanding the pool of potential bystanders.
POT1 Mutations Drive Lymphoid Malignancy Through Ultralong Telomeres
Pathogenic POT1 variants increase lymphoma risk eightfold by extending cellular longevity and promoting age-dependent clonal expansion.
Transradial Access Does Not Increase Radiation in Aneurysm Treatment
A comparative study finds no significant difference in radiation dose between radial and femoral routes for endovascular repair.