Social Media Addiction Linked to Hopelessness and Anhedonia in Youth
Network analysis identifies mood modification and conflict as key bridge symptoms connecting digital addiction to clinical distress.
Exercise Linked to Greater Mortality Reduction in Depressed Older Adults
A cohort study of 5323 seniors shows that physical activity provides a 32% mortality risk reduction for those with depressive symptoms.
Hypochondriasis Risk Increases with Genetic Relatedness in Large Cohort
A Swedish study of 5.8 million people finds full siblings of patients have a ninefold higher risk of health anxiety.
Polymer Sac Embolization Increases Aneurysm Regression After EVAR
A multicenter analysis shows shape memory polymer plugs improve one-year sac regression rates to 79% compared with 51% for standard repair.
Palliative Telecare Fails to Improve Goal Concordance in Cardiopulmonary Disease
A randomized trial of nurse and social worker-led phone interventions found no change in treatment alignment or patient uncertainty.
Low-Value Evaluation Increases Decision Thresholds and Neural Conflict in Choice Tasks
Shifting focus toward negative attributes slows evidence accumulation and increases attentional demand without altering final outcomes.
Specific RehaCom Modules Predict Processing Speed Gains in Progressive Multiple Sclerosis
Progression in attention-based modules and baseline characteristics like IQ and age determine cognitive outcomes in progressive MS.
NIRS-Guided Resuscitation Improves Early Motor Scores in Preterm Infants
A COSGOD III sub-study shows that monitoring cerebral oxygenation in the first 15 minutes of life correlates with better motor repertoire.
Targeted Agents Fail to Extend Survival in Pediatric Brainstem Glioma
The BIOMEDE trial finds no survival benefit for erlotinib, dasatinib, or everolimus, but identifies TP53 as a key prognostic marker.
Shared Mitochondrial Pathways Identified Across 23 Neurodevelopmental Risk Genes
Researchers used CRISPR to map how diverse genetic mutations converge on common molecular targets, allowing for drug testing in animal models.
Donor Factors and Platelet Degranulation Drive Whole Blood Antifibrinolytic Variability
A study of 28 whole blood units identifies distinct high and low PAI-1 activity cohorts linked to endothelial markers and storage lesions.
Balanced Fluids and Saline Show Similar Outcomes in Pediatric Septic Shock
A large trial of over 8,000 children found no difference in kidney events or mortality between balanced crystalloids and 0.9% saline.