Bicarbonate Reduces Renal Replacement Therapy in Critically Ill Adults
A meta-analysis of four randomized controlled trials indicates sodium bicarbonate significantly lowers the need for renal replacement therapy.
White Matter Microstructure Changes May Reflect Active Illness, Not Just Familial Risk
A large meta-analysis suggests that white matter abnormalities in schizophrenia and bipolar disorder are more tied to the disease process…
Dupilumab Reduces COPD Hospitalizations, ED Visits, and Corticosteroid Use
A pooled analysis of two phase 3 trials shows dupilumab significantly lowers healthcare utilization and corticosteroid burden in COPD patients.
Nebulized Heparin Linked to Reduced Mortality, More Ventilation-Free Days in Respiratory Failure
A meta-analysis suggests nebulized unfractionated heparin improves survival and ventilation-free days in adults with acute respiratory failure.
Psychotherapy Benefits for Depression Persist for Years, Meta-analysis Shows
A comprehensive meta-analysis clarifies the long-term trajectory of psychotherapy's effectiveness for adult depression, showing sustained benefits.
UK and Ireland Neonatal Stroke Incidence: 9.0 per 100,000 Live Births
A new surveillance study details the epidemiology, clinical patterns, and short-term outcomes of neonatal stroke in the UK and Ireland.
UK Neonatal Stroke Incidence: 9.0 per 100,000 Live Births, Varied Presentations
A new surveillance study details the incidence, clinical features, and initial management of neonatal stroke in the UK and Ireland.
Acute Kidney Injury Predicts Increased Risk of Stroke and Dementia
A meta-analysis of 11 million patients links acute renal insults to a 35% higher stroke risk and nearly fivefold 90-day poststroke mortality.
Digital Interventions Improve Eating Disorder Symptoms and Comorbid Mental Health
A meta-analysis of 36 trials shows digital tools offer consistent, durable benefits for core eating disorder symptoms and associated mental health con
Aerobic, Combined, and HIIT Exercise Lower Ambulatory Blood Pressure in Hypertension
A network meta-analysis clarifies the impact of various exercise types on 24-hour blood pressure in adults with hypertension.
Dementia With Lewy Bodies Incidence Rises Sharply After Age 65
A meta-analysis of population-based studies reveals significant age and sex disparities in dementia with Lewy bodies epidemiology.
Digitalis Reduces Worsening Heart Failure Events in Large Meta-Analysis
A study of 9,013 patients shows digitalis glycosides lower the risk of worsening heart failure events without affecting mortality.