NIRS-Guided Resuscitation Improves Early Motor Scores in Preterm Infants
A COSGOD III sub-study shows that monitoring cerebral oxygenation in the first 15 minutes of life correlates with better motor repertoire.
Targeted Agents Fail to Extend Survival in Pediatric Brainstem Glioma
The BIOMEDE trial finds no survival benefit for erlotinib, dasatinib, or everolimus, but identifies TP53 as a key prognostic marker.
Balanced Fluids and Saline Show Similar Outcomes in Pediatric Septic Shock
A large trial of over 8,000 children found no difference in kidney events or mortality between balanced crystalloids and 0.9% saline.
Neonatal Meconium Aspiration Increases Preschool Asthma Risk by 64 Percent
A retrospective cohort study of 326,940 children links neonatal lung injury from meconium aspiration to long-term respiratory morbidity.
Prenatal THC and Stress Synergistically Impair Maternal Care and Offspring Neurodevelopment
A mouse study finds combined prenatal exposures disrupt adolescent gene expression and behavior in a sex-specific manner.
Gingivoperiosteoplasty Matches Bone Grafting Success in Unilateral Clefts
A five-year retrospective study finds surgical outcomes for alveolar clefts depend on defect type and patient selection.
Psychosocial Screening at Intake Increases Comprehensive Care in Pediatric Psychiatry
Identifying family risk profiles through standardized tools helps clinicians tailor interventions and improve resource allocation for youth.
Children's Hospitals Delay Effective Surge Strategies Despite Tracking Occupancy
A national study shows a disconnect between capacity metrics and the operational triggers used to mitigate inpatient strain.
Chilean Pediatric Type 1 Diabetes Incidence Doubled Since 2007
A nationwide study shows a pandemic-era surge in new cases and diabetic ketoacidosis before a return to historical trends in 2022.
Physician-Led Program Improves Prehospital Care for Medically Complex Children
The STARS initiative uses individualized electronic care plans and targeted EMS training to reduce unnecessary hospital transports.
DSDO Lenses Reduce Axial Elongation More Than DIMS in Myopic Children
A multicenter study of 1,541 participants shows DSDO lenses also suppress physiological eye growth in non-myopic children over 12 months.
Oral Dysbiosis Linked to Systemic Inflammation and Autism Symptoms
Review identifies enrichment of Porphyromonas and Tannerella as potential drivers of neurodevelopmental patterns via the oral-brain axis.