Survival Improves for Leukemia Patients Requiring Mechanical Ventilation in the ICU
An individual participant data meta-analysis of 2003 patients shows declining mortality for ventilated adults with acute leukemia.
PREVENT and SCORE2 Equations Accurately Predict Global Cardiovascular Risk
A validation study of 6.4 million people confirms these risk models perform well across North America, Europe, and Asia.
Hippocampal Ripples Coordinate Cortical Planning Sequences in Epilepsy Patients
High-resolution intracranial recordings show that hippocampal ripples and neural replay drive the assembly of complex cognitive solutions.
Psychotherapy Shows Large, Durable Effects in Treatment-Resistant Depression
A reanalysis of trial data suggests clinical gains stem from simultaneous psychological shifts rather than sequential changes in defense.
Lifestyle and Psychological Factors Predict Pandemic-Era Depression in Older Adults
A longitudinal study identifies sleep disturbances and reduced physical activity as key drivers of increased depressive symptoms.
Stable Social Media Addiction Symptoms Link to Adolescent Anxiety and Depression
Longitudinal network analysis identifies tolerance and conflict as core drivers of digital dependency and comorbid internalizing disorders.
US Neurology Wait Times Average 50 Days Following Primary Care Referral
A retrospective analysis of 114,034 patients identifies significant delays for multiple sclerosis and regional disparities in access.
Photon-Counting CT Shows Higher Spatial Resolution for Lung Nodules in Phantom Study
New data suggest photon-counting technology maintains noise stability and resolution better than energy-integrating systems at low doses.
24-Hour Blood Pressure Variability Linked to Cognitive Decline and Brain Aging
Fluctuations in ambulatory blood pressure correlate with impaired executive function and blood-brain barrier leakage in older adults.
Fetal MRI Scoring System Quantifies Severity in Trisomy 13, 18, and CHARGE
A new morphological score and network analysis map phenotypic heterogeneity to assist in prenatal counseling and management planning.
Cutaneous pTDP-43 Deposits Distinguish ALS From Other Neuropathies
Skin and tongue biopsies detect phosphorylated TDP-43 pathology that correlates with clinical disease stage in patients with ALS.
Family Functioning Influences Prenatal Bonding Directly and via Depressive Symptoms
A multicenter study of 261 pregnant women shows that family dynamics shape the emotional quality of maternal-fetal attachment.