Plasma Tau and MRI Mismatch Identifies Rapid Alzheimer's Decline
Disproportionate brain atrophy relative to plasma ptau217 levels signals a vulnerable phenotype with faster cognitive loss and co-pathology.
All of Us Program Links 14 Years of Wearable Data to Clinical Records
A massive dataset connects Fitbit metrics from 59,000 participants to genomics and electronic health records for longitudinal research.
Chronic and Social Needs Linked to High School Absenteeism
A national study finds children with both chronic health conditions and social instability face a 9.4% risk of missing 11 or more school days.
Mild Acute Kidney Injury Minimally Affects Long-Term Kidney Function Decline
A study of 1,603 patients finds that mild to moderate AKI causes a small permanent drop in GFR without accelerating annual decline.
Cesium-131 Collagen Tiles Improve Local Control in Recurrent Meningioma
A phase 2 trial shows resection plus brachytherapy achieves 48% local control at five years for aggressive, recurrent meningiomas.
Helicopter Transport Increases Survival for Specific High-Risk Trauma Phenotypes
Patients with low Glasgow Coma Scale scores and respiratory distress show the greatest benefit from air medical evacuation.
Age Over 75 Does Not Increase Facelift Complication Risk
A 10-year retrospective study of 541 patients shows no significant rise in major or minor complications for patients aged 76 and older.
Gut Microbiome Linked to Macrocephaly in NF1 Mouse Model
Sex-specific microbial signatures correlate with brain size and autism-like behaviors in mice with Neurofibromatosis type 1 mutations.
UK Data Support Immunoglobulin-Free Maintenance After Liver Transplant
A retrospective study of 273 patients shows that long-term immunoglobulin does not reduce hepatitis B recurrence or improve survival.
Imaging Score Predicts Survival in Node-Negative Esophageal Cancer
A temporal lymph node stratification score identifies high-risk patients who may benefit from adjuvant therapy after neoadjuvant treatment.
Low CSF Amyloid-Beta Predicts Intracranial Hemorrhage in CAA Patients
Low levels of amyloid-beta 40 and 42 in cerebrospinal fluid are associated with a sevenfold increase in future symptomatic bleeding risk.
PD-1 Inhibitors Improve Survival in First-Line NK/T-Cell Lymphoma Treatment
Adding PD-1 inhibitors to asparaginase-based therapy reduces mortality risk by 45 percent in patients with high-risk extranodal disease.