Non-Randomized Controlled Trial
32 articles tagged "Non-Randomized Controlled Trial"
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Venetoclax Plus Chemotherapy Improves MRD Response, Survival in Ph-Negative ALL
A phase 2 study shows venetoclax combined with pediatric-inspired chemotherapy enhances outcomes for newly diagnosed adolescents and adults.
AI 3D Morphing Reduces Revisions, Improves Outcomes in African American Rhinoplasty
A study of 392 patients found AI 3D morphing in rhinoplasty led to fewer revisions and better aesthetic and psychosocial scores.
Sternal Vibration Plus Mindfulness Improves Body Awareness, White Matter in Trauma
A study in trauma-exposed adults found sternal vibration combined with mindfulness meditation enhanced interoceptive awareness and increased neurite.
ED Nudge Strategy Increases Naltrexone Prescribing for Alcohol Misuse
A multicomponent emergency department protocol significantly raised naltrexone initiation for patients with alcohol-related diagnoses.
NXT007 Reaches Nonhemophilic Factor VIII Levels in Severe Hemophilia A
A phase 1/2 trial shows monthly subcutaneous NXT007 achieves factor activity above 40 IU/dL and eliminates bleeds at higher doses.
Prostate SBRT Maintains 90% Relapse-Free Survival at Ten Years
A multi-center trial of 310 patients shows low- and intermediate-risk prostate cancer control remains durable with minimal late toxicity.
Prophylactic Antiemetics Fail to Reduce Opioid-Induced Nausea in Prehospital Trauma
A prospective study of 205 HEMS patients shows no benefit for routine intravenous ondansetron or isopropanol aromatherapy.
Nerve Monitoring Reduces Neurapraxia and Dissection Time in Complex Facelifts
A prospective study of 200 patients shows intraoperative monitoring prevents nerve injury and halves operative time in secondary cases.
Autologous Mesenchymal Cells Reduce Neuroinflammation in Chronic Brain Injury
A Phase 1/2a trial shows intravenous stromal cells improve white matter integrity and reduce immune cell density in the chronic TBI brain.
Prophylactic Lymphatic Reconstruction Reduces Lymphedema Risk in Gynecologic Cancer
Simultaneous lymph node-to-vein anastomosis lowered the one-year incidence of lower extremity lymphedema from 49 percent to 8 percent.
Automated Ventilation Maintains Target Minute Volume in Helicopter Rescue Simulation
A crossover study shows automated ventilators achieve target ventilation more consistently than manual bagging during short-haul transport.
Sentinel Node Biopsy Reduces Axillary Dissection in cN1 Breast Cancer
A clinical trial shows 76% of patients with palpable nodes and HR+/HER2- disease can avoid full dissection using upfront biopsy.