The Briefing · Emergency & Critical Care
Continuous newsroom coverage of evidence in Emergency & Critical Care — newest first.
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Plain X-rays and Physical Exam Reliably Screen Pediatric Thoracolumbar Injuries
A multicenter study suggests dedicated spinal X-rays and physical exam can reduce unnecessary CT scans in children with potential spinal trauma.
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Brazilian Study Pinpoints Persistent Critical Illness Onset at ICU Day 15
A large cohort study in Brazil identifies the transition to persistent critical illness at 15 days, impacting resource utilization.
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Waveform-Derived 60-Second ROSC Definition Accurately Identifies Transient Events
A prospective validation study confirms a specific defibrillator waveform criterion reliably detects transient return of spontaneous circulation.
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CBD's Pain Modulation Effects Vary by Opioid Dosing Timing in OUD Patients
A crossover study reveals cannabidiol's impact on pain sensitivity is dependent on whether opioid agonist treatment has been administered.
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MMAE for cSDH: Resolution Trajectories and Functional Outcomes Quantified
A large multicenter study details the temporal patterns of hematoma reduction and functional recovery after middle meningeal artery embolization.
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AI Algorithm Continuously Monitors Inspiratory Muscle Effort, Patient-Ventilator Synchrony
A new AI algorithm offers a noninvasive, real-time method for assessing inspiratory muscle pressure and detecting dyssynchronies in mechanically…
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ICP Monitoring Linked to Lower 30-Day Mortality in Kenyan Severe TBI Patients
A retrospective cohort study in a low- and middle-income country found intracranial pressure monitoring associated with reduced mortality.
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Helicopter Transport Expands ECPR Access for Rural Refractory Cardiac Arrest
A HEMS-facilitated ECPR pathway safely extends advanced resuscitation to rural areas, maintaining neurologic outcomes comparable to ground transport.
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Massive Transfusion Reduces Vancomycin Levels in Swine Model
A swine study indicates that prophylactic vancomycin may become subtherapeutic after four units of whole-blood resuscitation.
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Unhealthy Diet Linked to T17-High Asthma in Puerto Rican Youth
A study in Puerto Rican children and adolescents found an unhealthy dietary pattern increases the odds of T17-high asthma.
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Low-Level FLT3-ITD Microclones Increase Relapse Risk in AML
A post-hoc analysis reveals that FLT3-ITD microclones carry a similar relapse risk to macroclones in young adults with acute myeloid leukemia.
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Real-Time Subphenotyping for ARDS and AHRF Achieves Feasibility Threshold
A multicenter US study demonstrates the ability to rapidly classify patients with acute respiratory distress syndrome into biological subphenotypes.
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HERMES-24 Score Predicts Outcomes in Real-World Late-Window LVO Patients
A German registry study validates the HERMES-24 score for 90-day functional outcome prediction after endovascular therapy for large vessel occlusion.
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Bridging Stent Patency Varies by Type and Renal Artery Location in F/BEVAR
A single-center study of over 1100 bridging stent grafts identifies specific devices and anatomical sites linked to lower midterm patency.
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Multimodal Training Improves Pediatric CPR Depth, Rate Compliance in ED
A quality improvement initiative in a pediatric emergency department enhances chest compression metrics through integrated coach and compressor…
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Venetoclax Plus Chemotherapy Improves MRD Response, Survival in Ph-Negative ALL
A phase 2 study shows venetoclax combined with pediatric-inspired chemotherapy enhances outcomes for newly diagnosed adolescents and adults.
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Pediatric SAKI Subphenotypes Predict Outcomes, Inform Treatment Responses
Distinct subphenotypes of pediatric sepsis-associated acute kidney injury show varying severity, molecular profiles, and responses…
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Gut Microbiota Linked to IPF Severity, Survival, and Treatment Response
A study in 411 patients with idiopathic pulmonary fibrosis identifies specific gut microbial associations with disease progression and treatment.
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Consensus Checklist and Passing Standard for Brain Death Competency
A Delphi and Angoff process established a 98-item checklist and an 89% minimum passing score for BD/DNC determination.
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Germline Variants Linked to Increased Cancer Risk in Pediatric Patients
A large-scale analysis of pediatric exome sequencing data reveals specific germline variants significantly elevate future cancer incidence.
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Delayed Awakening After Cardiac Arrest: Prognostic Implications and Recovery Potential
A scoping review highlights variable definitions and the potential for good neurological recovery despite delayed awakening after OHCA.
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Expert Consensus Guides 1.1 mm Cryoprobe Use in Non-ILD Transbronchial Biopsy
An international Delphi panel established 31 consensus statements for transbronchial cryobiopsy in non-interstitial lung disease.
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Population Screening Identifies Early Type 1 Diabetes in Children, Quantifies Progression
A large-scale study in Bavaria, Germany, reveals the prevalence and progression rates of presymptomatic type 1 diabetes in a general pediatric…